Revolutionize Veterinary Analyses with BMA Porcine Tissue Monoclonal Antibodies
Dear Readers,
Porcine animal models are used in research due to their anatomical, physiological and immunological similarity to humans. They have a complete set of innate and adaptive immune effectors and share structural and functional similarities of most immune system proteins with humans. In fact, approximately 80% of the functions of their immune system are similar to those of humans, unlike the mouse immune system, which is only 10% similar.
The availability of genomic and proteomic tools for analysing this species makes it possible to apply the porcine as a model for transplantation studies, toxicology and pharmacology, as well as for stem cell therapies and microbial infectious diseases.
These characteristics underline how pigs represent a valuable intermediate species for evaluating disease knowledge that could be applicable to the study of human diseases.
Here at BMA, we develop antibodies specifically designed for use with porcine tissues, recognizing the crucial role this species plays in animal models and in studying diseases impacting human health. Our aim is to provide a comprehensive range of antibodies to support your assessment of veterinary tissue samples. For example:
Monoclonal Antibody to Porcine Epithelial Basement Cells Mouse lgM, Clone PB1
Monoclonal antibody PB1 recognizes cells of the epithelial basement cell layer in different swine organs. Positive staining is seen with basal cells in the epidermis of the skin, in bronchiolar epithelia of the lung and in cells of the macula densa in the kidney. Antibody PB1 cross-reacts with human tissues and works with frozen and paraffin sections.
Monoclonal Antibody to Porcine Mx1 Protein Mouse lgG1 κ, Clone AM39
Monoclonal antibody AM39 recognizes the porcine Mx1 protein. Mx proteins are cytoplasmic proteins induced by type-1 interferons (alpha and beta). ln humans, mainly monocytes and lymphocytes have been shown to express the Mx protein, whereas Mx expression is low in granulocytes. Mx proteins are high molecular weight GTPases of 70- 80kD which belong to the dynamin superfamily. A unique property is their antiviral activity against many RNA viruses.
Our anti-porcine antibodies are monoclonal and produced by affinity purification. They are tested and validated in-house, suitable for a range of applications listed on the product datasheet including, immunohistochemistry, western blotting, immunofluorescence, FACs, and ELISA.
Unlock the future of veterinary analyses with our cutting-edge porcine tissue monoclonal antibodies! Designed for unparalleled precision and reliability, our antibodies are transforming veterinary analyses across the globe.
Check out our catalog and get in contact with us at info@bma.ch
We Iook forward to meeting your Iaboratory needs!
Author: Dr. Sonia Accossato
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